N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial

Mechanism-based treatments for schizophrenia are needed, and increasing evidence suggests that oxidative stress may be a target. Previous research has shown that N-acetylcysteine (NAC), an antioxidant and glutathione (GSH) precursor almost devoid of side effects, improved negative symptoms, decrease...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Klauser, Paul, Xin, Lijing, Fournier, Margot, Griffa, Alessandra, Cleusix, Martine, Jenni, Raoul, Cuenod, Michel, Gruetter, Rolf, Hagmann, Patric, Conus, Philippe, Baumann, Philipp S., Do, Kim Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185923/
https://ncbi.nlm.nih.gov/pubmed/30315150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0266-8
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