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Role of 5-HT(1A) Receptor Stimulation in the Medial Prefrontal Cortex in the Sustained Antidepressant Effects of Ketamine

BACKGROUND: We previously reported that serotonergic transmission plays an important role in antidepressant effects of ketamine. However, detailed mechanisms have not been elucidated. Among the serotonin receptor subtypes, the serotonin(1A) receptor in the medial prefrontal cortex has an important r...

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Pubblicato in:Int J Neuropsychopharmacol
Autori principali: Fukumoto, Kenichi, Iijima, Michihiko, Funakoshi, Takeo, Chaki, Shigeyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888010/
https://ncbi.nlm.nih.gov/pubmed/29309585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx116
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