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Role of 5-HT(1A) Receptor Stimulation in the Medial Prefrontal Cortex in the Sustained Antidepressant Effects of Ketamine

BACKGROUND: We previously reported that serotonergic transmission plays an important role in antidepressant effects of ketamine. However, detailed mechanisms have not been elucidated. Among the serotonin receptor subtypes, the serotonin(1A) receptor in the medial prefrontal cortex has an important r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Neuropsychopharmacol
Hauptverfasser: Fukumoto, Kenichi, Iijima, Michihiko, Funakoshi, Takeo, Chaki, Shigeyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888010/
https://ncbi.nlm.nih.gov/pubmed/29309585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx116
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