Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation

We recently found that FOXO1 repression contributes to the oncogenic program of classical Hodgkin lymphoma (cHL). Interestingly, FOXO3A, another member of the FOXO family, was reported to be expressed in the malignant Hodgkin and Reed-Sternberg cells of cHL at higher levels than in non-Hodgkin lymph...

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Vydáno v:Blood
Hlavní autoři: Osswald, Clarissa D., Xie, Linka, Guan, Hanfeng, Herrmann, Franziska, Pick, Sarah M., Vogel, Marion J., Gehringer, Franziska, Chan, Fong Chun, Steidl, Christian, Wirth, Thomas, Ushmorov, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887767/
https://ncbi.nlm.nih.gov/pubmed/29439954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-795278
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