Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation

We recently found that FOXO1 repression contributes to the oncogenic program of classical Hodgkin lymphoma (cHL). Interestingly, FOXO3A, another member of the FOXO family, was reported to be expressed in the malignant Hodgkin and Reed-Sternberg cells of cHL at higher levels than in non-Hodgkin lymph...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Osswald, Clarissa D., Xie, Linka, Guan, Hanfeng, Herrmann, Franziska, Pick, Sarah M., Vogel, Marion J., Gehringer, Franziska, Chan, Fong Chun, Steidl, Christian, Wirth, Thomas, Ushmorov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2018
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887767/
https://ncbi.nlm.nih.gov/pubmed/29439954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-795278
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