A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart

Chromatin remodelling precedes transcriptional and structural changes in heart failure. A body of work suggests roles for the developmental Wnt signalling pathway in cardiac remodelling. Hitherto, there is no evidence supporting a direct role of Wnt nuclear components in regulating chromatin landsca...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Iyer, Lavanya M, Nagarajan, Sankari, Woelfer, Monique, Schoger, Eric, Khadjeh, Sara, Zafiriou, Maria Patapia, Kari, Vijayalakshmi, Herting, Jonas, Pang, Sze Ting, Weber, Tobias, Rathjens, Franziska S, Fischer, Thomas H, Toischer, Karl, Hasenfuss, Gerd, Noack, Claudia, Johnsen, Steven A, Zelarayán, Laura C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887416/
https://ncbi.nlm.nih.gov/pubmed/29394407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky049
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