Translational profiling of B cells infected with the Epstein-Barr virus reveals 5′ leader ribosome recruitment through upstream open reading frames

The Epstein-Barr virus (EBV) genome encodes several hundred transcripts. We have used ribosome profiling to characterize viral translation in infected cells and map new translation initiation sites. We show here that EBV transcripts are translated with highly variable efficiency, owing to variable t...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Bencun, Maja, Klinke, Olaf, Hotz-Wagenblatt, Agnes, Klaus, Severina, Tsai, Ming-Han, Poirey, Remy, Delecluse, Henri-Jacques
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Data Resources and Analyses
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887285/
https://ncbi.nlm.nih.gov/pubmed/29529302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky129
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