Translational profiling of B cells infected with the Epstein-Barr virus reveals 5′ leader ribosome recruitment through upstream open reading frames

The Epstein-Barr virus (EBV) genome encodes several hundred transcripts. We have used ribosome profiling to characterize viral translation in infected cells and map new translation initiation sites. We show here that EBV transcripts are translated with highly variable efficiency, owing to variable t...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Bencun, Maja, Klinke, Olaf, Hotz-Wagenblatt, Agnes, Klaus, Severina, Tsai, Ming-Han, Poirey, Remy, Delecluse, Henri-Jacques
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Data Resources and Analyses
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887285/
https://ncbi.nlm.nih.gov/pubmed/29529302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky129
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