Translational profiling of B cells infected with the Epstein-Barr virus reveals 5′ leader ribosome recruitment through upstream open reading frames

The Epstein-Barr virus (EBV) genome encodes several hundred transcripts. We have used ribosome profiling to characterize viral translation in infected cells and map new translation initiation sites. We show here that EBV transcripts are translated with highly variable efficiency, owing to variable t...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Bencun, Maja, Klinke, Olaf, Hotz-Wagenblatt, Agnes, Klaus, Severina, Tsai, Ming-Han, Poirey, Remy, Delecluse, Henri-Jacques
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Data Resources and Analyses
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887285/
https://ncbi.nlm.nih.gov/pubmed/29529302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky129
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