IL-6 blockade in systemic juvenile idiopathic arthritis – achievement of inactive disease and remission (data from the German AID-registry)

BACKGROUND: Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with an autoinflammatory component of unknown etiology related to the innate immune system. A major role in the pathogenesis has been ascribed to proinflammatory cytokines like interleukin-6 (IL-6), and effective drugs in...

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Vydáno v:Pediatr Rheumatol Online J
Hlavní autoři: Bielak, M., Husmann, E., Weyandt, N., Haas, J.-P., Hügle, B., Horneff, G., Neudorf, U., Lutz, T., Lilienthal, E., Kallinich, T., Tenbrock, K., Berendes, R., Niehues, T., Wittkowski, H., Weißbarth-Riedel, E., Heubner, G., Oommen, P., Klotsche, J., Foell, Dirk, Lainka, E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887199/
https://ncbi.nlm.nih.gov/pubmed/29622022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-018-0236-y
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