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Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry

BACKGROUND: Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with dysregulation of the innate immune system driven by cytokines. A major role is ascribed to interleukin-1β (IL-1β), supporting the autoinflammatory character of the disease and offering an effective blocking mechanism...

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Bibliographic Details
Published in:Pediatr Rheumatol Online J
Main Authors: Lainka, Elke, Baehr, Melanie, Raszka, Bernadette, Haas, Johannes-Peter, Hügle, Boris, Fischer, Nadine, Foell, Dirk, Hinze, Claas, Weissbarth-Riedel, Elisabeth, Kallinich, Tilmann, Horneff, Gerd, Windschall, Daniel, Lilienthal, Eggert, Niehues, Tim, Neudorf, Ulrich, Berendes, Rainer, Küster, Rolf-Michael, Oommen, Prasad Thomas, Rietschel, Christoph, Lutz, Thomas, Weller-Heinemann, Frank, Tenbrock, Klaus, Heubner, Georg Leonhard, Klotsche, Jens, Wittkowski, Helmut
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986520/
https://ncbi.nlm.nih.gov/pubmed/33752669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-021-00510-8
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