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Mito-Nuclear Interactions Affecting Lifespan and Neurodegeneration in a Drosophila Model of Leigh Syndrome

Proper mitochondrial activity depends upon proteins encoded by genes in the nuclear and mitochondrial genomes that must interact functionally and physically in a precisely coordinated manner. Consequently, mito-nuclear allelic interactions are thought to be of crucial importance on an evolutionary s...

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Vydáno v:Genetics
Hlavní autoři: Loewen, Carin A., Ganetzky, Barry
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887147/
https://ncbi.nlm.nih.gov/pubmed/29496745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300818
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