The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

Hypermethylated-in-Cancer 1 (Hic1) is a tumor suppressor gene frequently inactivated by epigenetic silencing and loss-of-heterozygosity in a broad range of cancers. Loss of HIC1, a sequence-specific zinc finger transcriptional repressor, results in deregulation of genes that promote a malignant phen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Szczepny, Anette, Carey, Kirstyn, McKenzie, Lisa, Jayasekara, W. Samantha N., Rossello, Fernando, Gonzalez-Rajal, Alvaro, McCaw, Andrew S., Popovski, Dean, Wang, Die, Sadler, Anthony J., Mahar, Annabelle, Russell, Prudence A., Wright, Gavin, McCloy, Rachael A., Garama, Daniel J., Gough, Daniel J., Baylin, Stephen B., Burgess, Andrew, Cain, Jason E., Watkins, D. Neil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Brief Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886987/
https://ncbi.nlm.nih.gov/pubmed/29367758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0022-1
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