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The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines

The ability of high-risk HPV E6 oncoproteins to target cellular proteins which harbor PDZ domains is believed to play an important role in the virus life cycle and to influence the ability of these viruses to bring about malignant transformation. Whilst many of these PDZ proteins are potential tumou...

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Bibliographic Details
Published in:Papillomavirus Res
Main Authors: Kranjec, Christian, Tomaić, Vjekoslav, Massimi, Paola, Nicolaides, Lietta, Doorbar, John, Banks, Lawrence
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886876/
https://ncbi.nlm.nih.gov/pubmed/29074188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pvr.2016.04.001
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