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Linear assembly of a human centromere on the Y chromosome
The human genome reference sequence remains incomplete owing to the challenge of assembling long tracts of near-identical tandem repeats in centromeres. We implemented a nanopore sequencing strategy to generate high-quality reads that span hundreds of kilobases of highly repetitive DNA in a human Y...
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| Publicado no: | Nat Biotechnol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group US
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886786/ https://ncbi.nlm.nih.gov/pubmed/29553574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4109 |
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