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TTR Stabilizers are Associated with Improved Survival in Patients with Transthyretin Cardiac Amyloidosis

BACKGROUND: Transthyretin cardiac amyloidosis (TTR-CA) is caused by dissociation of transthyretin (TTR) into monomers, which misassemble into amyloid fibrils. TTR stabilizers act at the dimer-dimer interface to prevent dissociation. We investigated differences in survival among patients with TTR-CA...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Rosenblum, Hannah, Castano, Adam, Alvarez, Julissa, Goldsmith, Jeff, Helmke, Stephen, Maurer, Mathew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886729/
https://ncbi.nlm.nih.gov/pubmed/29615436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004769
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