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Phenotype and biochemical heterogeneity in late onset Fabry disease defined by N215S mutation

BACKGROUND: Fabry disease (FD) results from X-linked inheritance of a mutation in the GLA gene, encoding for alpha galactosidase A, and is characterized by heterogeneous clinical manifestations. Two phenotypes have been described “Classic” and “late onset” which cannot be predicted exclusively by ge...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Lavalle, L., Thomas, A. S., Beaton, B., Ebrahim, H., Reed, M., Ramaswami, U., Elliott, P., Mehta, A. B., Hughes, D. A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886405/
https://ncbi.nlm.nih.gov/pubmed/29621274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193550
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