Nalaganje...

The female epilepsy protein PCDH19 is a new GABA(A)R-binding partner that regulates GABAergic transmission as well as migration and morphological maturation of hippocampal neurons

The PCDH19 gene (Xp22.1) encodes the cell-adhesion protein protocadherin-19 (PCDH19) and is responsible for a neurodevelopmental pathology characterized by female-limited epilepsy, cognitive impairment and autistic features, the pathogenic mechanisms of which remain to be elucidated. Here, we identi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Bassani, Silvia, Cwetsch, Andrzej W, Gerosa, Laura, Serratto, Giulia M, Folci, Alessandra, Hall, Ignacio F, Mazzanti, Michele, Cancedda, Laura, Passafaro, Maria
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886308/
https://ncbi.nlm.nih.gov/pubmed/29360992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy019
Oznake: Označite
Brez oznak, prvi označite!