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Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells

A recurring challenge in cell biology is to define the molecular components of macromolecular complexes of interest. The predominant method, immunoprecipitation, recovers only strong interaction partners that survive cell lysis and repeated detergent washes. We explored peroxidase-catalyzed proximit...

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Dades bibliogràfiques
Publicat a:Cell Chem Biol
Autors principals: Han, Shuo, Udeshi, Namrata D., Deerinck, Thomas J., Svinkina, Tanya, Ellisman, Mark H., Carr, Steven A., Ting, Alice Y.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886301/
https://ncbi.nlm.nih.gov/pubmed/28238724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.02.002
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