Loss of CHCHD10–CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS

Coiled-helix coiled-helix domain containing protein 10 (CHCHD10) and its paralogue CHCHD2 belong to a family of twin CX(9)C motif proteins, most of which localize to the intermembrane space of mitochondria. Dominant mutations in CHCHD10 cause amyotrophic lateral sclerosis (ALS)/frontotemporal dement...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Straub, Isabella R, Janer, Alexandre, Weraarpachai, Woranontee, Zinman, Lorne, Robertson, Janice, Rogaeva, Ekaterina, Shoubridge, Eric A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886208/
https://ncbi.nlm.nih.gov/pubmed/29121267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx393
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker