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Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype
Cell Division Cycle 6 (Cdc6) is a component of pre-replicative complex (preRC) forming on DNA replication origins in eukaryotes. Recessive mutations in ORC1, ORC4, ORC6, CDT1 or CDC6 of the preRC in human cause Meier-Gorlin syndrome (MGS) that is characterized by impaired post-natal growth, short st...
Guardat en:
| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886151/ https://ncbi.nlm.nih.gov/pubmed/28985365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx305 |
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