Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease

IMPORTANCE: Genetic factors have a well-known influence on Parkinson disease (PD) susceptibility. The largest genome-wide association study (GWAS) identified 26 independent single-nucleotide polymorphisms (SNPs) associated with PD risk. Among patients, the course and severity of symptom progression...

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Dades bibliogràfiques
Publicat a:JAMA Neurol
Autors principals: Paul, Kimberly C., Schulz, Jessica, Bronstein, Jeff M., Lill, Christina M., Ritz, Beate R.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2018
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885856/
https://ncbi.nlm.nih.gov/pubmed/29340614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.4206
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