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The Pharmacology of CD38/NADase: An emerging target for cancer and aging diseases

Recent reports indicate that intracellular levels of NAD decline in tissues during chronological aging, and that therapies aim at increasing cellular NAD levels could have beneficial effects in many age-related diseases. The protein CD38 (CLUSTER OF DIFFERENTIATION 38) is a multifunctional enzyme th...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Chini, Eduardo N., Chini, Claudia C.S., Netto, Jair Machado Espindola, de Oliveira, Guilherme C., van Schooten, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885288/
https://ncbi.nlm.nih.gov/pubmed/29482842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.02.001
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