Comparison of Residual Risk–Based Eligibility vs Tumor Size and Nodal Status for Power Estimates in Adjuvant Trials of Breast Cancer Therapies

IMPORTANCE: Many large adjuvant clinical trials end up underpowered because of fewer than expected events in the control arm. Ensuring a minimum number of events would result in more informative trials. OBJECTIVE: To calculate individualized residual risk estimates using residual risk prediction sof...

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Publicado en:JAMA Oncol
Autores principales: Wei, Wei, Kurita, Tomoko, Hess, Kenneth R., Sanft, Tara, Szekely, Borbala, Hatzis, Christos, Pusztai, Lajos
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2018
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885272/
https://ncbi.nlm.nih.gov/pubmed/29372234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.5092
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