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Functional germline variants as potential co-oncogenes

Germline variants that affect the expression or function of proteins contribute to phenotypic variation in humans and likely determine individual characteristics and susceptibility to diseases including cancer. A number of high penetrance germline variants that increase cancer risk have been identif...

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Détails bibliographiques
Publié dans:NPJ Breast Cancer
Auteurs principaux: Agarwal, Divyansh, Nowak, Christoph, Zhang, Nancy R., Pusztai, Lajos, Hatzis, Christos
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700137/
https://ncbi.nlm.nih.gov/pubmed/29177190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0051-5
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