Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease

IMPORTANCE: Alzheimer disease (AD) develops during several decades. Presymptomatic individuals might be the best candidates for clinical trials, but their identification is challenging because they have no symptoms. OBJECTIVE: To assess whether a sporadic parental estimated years to symptom onset ca...

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Dettagli Bibliografici
Pubblicato in:JAMA Neurol
Autori principali: Villeneuve, Sylvia, Vogel, Jacob W., Gonneaud, Julie, Pichet Binette, Alexa, Rosa-Neto, Pedro, Gauthier, Serge, Bateman, Randall J., Fagan, Anne M., Morris, John C., Benzinger, Tammie L. S., Johnson, Sterling C., Breitner, John C. S., Poirier, Judes
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2018
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885216/
https://ncbi.nlm.nih.gov/pubmed/29482212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.5135
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