Cutting an NKG2D Ligand Short: Cellular Processing of the Peculiar Human NKG2D Ligand ULBP4

Stress-induced cell surface expression of MHC class I-related glycoproteins of the MIC and ULBP families allows for immune recognition of dangerous “self cells” by human cytotoxic lymphocytes via the NKG2D receptor. With two MIC molecules (MICA and MICB) and six ULBP molecules (ULBP1–6), there are a...

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Udgivet i:Front Immunol
Main Authors: Zöller, Tobias, Wittenbrink, Mareike, Hoffmeister, Meike, Steinle, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884875/
https://ncbi.nlm.nih.gov/pubmed/29651291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00620
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