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Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors

Immunosuppression is a typical hallmark of cancer and frequently includes perturbations of the NKG2D tumor recognition system as well as impaired signaling by other activating NK cell receptors. Several in vitro studies suggested that sustained engagement of the NKG2D receptor, as it is occurring in...

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Vydáno v:Front Immunol
Hlavní autoři: Koch, Christine, Kim, Younghoon, Zöller, Tobias, Born, Christina, Steinle, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675847/
https://ncbi.nlm.nih.gov/pubmed/29163533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01466
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