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Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors

Immunosuppression is a typical hallmark of cancer and frequently includes perturbations of the NKG2D tumor recognition system as well as impaired signaling by other activating NK cell receptors. Several in vitro studies suggested that sustained engagement of the NKG2D receptor, as it is occurring in...

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Publicat a:Front Immunol
Autors principals: Koch, Christine, Kim, Younghoon, Zöller, Tobias, Born, Christina, Steinle, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675847/
https://ncbi.nlm.nih.gov/pubmed/29163533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01466
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