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Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus

The persistent public health threat of infection with Middle East respiratory syndrome coronavirus (MERS-CoV) highlights the need for an effective and safe MERS-CoV vaccine. In this study, we prepared and vaccinated mice with either a Spike (S) protein or inactivated whole MERS-CoV (IV) with a combi...

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Detaylı Bibliyografya
Yayımlandı:Emerg Microbes Infect
Asıl Yazarlar: Deng, Yao, Lan, Jiaming, Bao, Linlin, Huang, Baoying, Ye, Fei, Chen, Yingzhu, Yao, Yanfeng, Wang, Wenling, Qin, Chuan, Tan, Wenjie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884803/
https://ncbi.nlm.nih.gov/pubmed/29618723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0056-7
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