Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma

Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are i...

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Publicado no:Bone Res
Main Authors: Chen, Demeng, Zhao, Zhiqiang, Huang, Zixin, Chen, Du-Chu, Zhu, Xin-Xing, Wang, Yi-Ze, Yan, Ya-Wei, Tang, Shaojun, Madhavan, Subha, Ni, Weiyi, Huang, Zhan-peng, Li, Wen, Ji, Weidong, Shen, Huangxuan, Lin, Shuibin, Jiang, Yi-Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884797/
https://ncbi.nlm.nih.gov/pubmed/29644114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0009-8
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