Spatially resolved and quantitative analysis of VISTA/PD-1H as a novel immunotherapy target in human non-small cell lung cancer

PURPOSE: Determine the localized expression pattern and clinical significance of VISTA/PD-1H in human NSCLC. EXPERIMENTAL DESIGN: Using multiplex quantitative immunofluorescence (QIF), we performed localized measurements of VISTA, PD-1 and PD-L1 protein in 758 stage I-IV NSCLCs from 3 independent co...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Villarroel-Espindola, Franz, Yu, Xiaoqing, Datar, Ila, Mani, Nikita, Sanmamed, Miguel, Velcheti, Vamsidhar, Syrigos, Konstantinos, Toki, Maria, Zhao, Hongyu, Chen, Lieping, Herbst, Roy S., Schalper, Kurt A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884702/
https://ncbi.nlm.nih.gov/pubmed/29203588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2542
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