Cargando...
A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad
One group of enzymes that confer resistance to aminoglycoside antibiotics through covalent modification belongs to the GCN5-related N-acetyltransferase (GNAT) superfamily. We show how a unique GNAT subfamily member uses a previously unidentified noncanonical catalytic triad, consisting of a glutamic...
Gardado en:
| Publicado en: | Sci Adv |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884680/ https://ncbi.nlm.nih.gov/pubmed/29632894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aas8667 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|