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Sumoylation promotes optimal APC/C activation and timely anaphase
The Anaphase Promoting Complex/Cyclosome (APC/C) is a ubiquitin E3 ligase that functions as the gatekeeper to mitotic exit. APC/C activity is controlled by an interplay of multiple pathways during mitosis, including the spindle assembly checkpoint (SAC), that are not yet fully understood. Here, we s...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884673/ https://ncbi.nlm.nih.gov/pubmed/29517484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29539 |
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