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CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

High grade serous ovarian cancer (HGSOC) is a disease with a high relapse rate and poor overall survival despite good initial responses to platinum-based therapy. Cell cycle inhibition with targeted CDK4/6 inhibitors is a new therapeutic approach showing promise as a maintenance therapy in cancer. A...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Iyengar, Mangala, O’Hayer, Patrick, Cole, Alex, Sebastian, Tara, Yang, Kun, Coffman, Lan, Buckanovich, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884655/
https://ncbi.nlm.nih.gov/pubmed/29644000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24585
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