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Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice
Primary liver cancer is the 3rd leading cause of cancer deaths worldwide with very few effective treatments. Sphingosine kinase 1 (SphK1), a key regulator of sphingolipid metabolites, is over-expressed in human hepatocellular carcinoma (HCC) and our previous studies have shown that SphK1 is importan...
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| 發表在: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884653/ https://ncbi.nlm.nih.gov/pubmed/29643998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24583 |
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