Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways

Glucose-regulated protein 78 (GRP78), an ER chaperone, is overexpressed in cancer cells. Solid tumor cells can secrete GRP78 that can promote tumor angiogenesis, differentiation of bone marrow-derived mesenchymal stem cells, tumor cell proliferation and polarization of tumor-associated macrophages....

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Bibliographic Details
Published in:Oncotarget
Main Authors: La, Xiaoqin, Zhang, Lichao, Li, Hanqing, Li, Zhuoyu, Song, Guisheng, Yang, Peng, Yang, Yufei
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884641/
https://ncbi.nlm.nih.gov/pubmed/29643986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24090
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