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Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells

BACKGROUND: Targeted therapies for cancer, especially the malignant cancer, are always restricted by the deficiency of tumor-specific drug delivery methods. Subtilase cytotoxic is a virulent cytotoxin, and the subunit A (SubA) of it is able to destroy the structure of glucose-regulated protein 78 (G...

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Vydáno v:BMC Biotechnol
Hlavní autoři: Zhang, Lichao, Li, Zongwei, Shi, Tonglin, La, Xiaoqin, Li, Hanqing, Li, Zhuoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009487/
https://ncbi.nlm.nih.gov/pubmed/27585649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0294-5
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