Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence

Esophageal cancer occurs as either squamous cell carcinoma (ESCC) or adenocarcinoma. ESCCs comprise almost 90% of cases worldwide, and recur with a less than 15% five-year survival rate despite available treatments. The identification of new ESCC drivers and therapeutic targets is critical for impro...

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Publicado en:PLoS Genet
Autores principales: Matrka, Marie C., Cimperman, Katherine A., Haas, Sarah R., Guasch, Geraldine, Ehrman, Lisa A., Waclaw, Ronald R., Komurov, Kakajan, Lane, Adam, Wikenheiser-Brokamp, Kathryn A., Wells, Susanne I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884580/
https://ncbi.nlm.nih.gov/pubmed/29538372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007227
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