PD-1/PD-L1 expression in a series of intracranial germinoma and its association with Foxp3+ and CD8+ infiltrating lymphocytes

One histopathological characteristic of intracranial germinoma is abundant tumor-infiltrating lymphocytes (TILs) showing a two-cell pattern with large undifferentiated tumor cells. The programmed cell death 1 (PD-1)/programmed cell death 1 ligand (PD-L) axis has recently been recognized as an anti-t...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Bin, Arakawa, Yoshiki, Yokogawa, Ryuta, Tokunaga, Shinya, Terada, Yukinori, Murata, Daiki, Matsui, Yasuzumi, Fujimoto, Ko-ichi, Fukui, Nobuyuki, Tanji, Masahiro, Mineharu, Yohei, Minamiguchi, Sachiko, Miyamoto, Susumu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884516/
https://ncbi.nlm.nih.gov/pubmed/29617441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194594
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