In Vivo 6-([(18)F]Fluoroacetamido)-1-hexanoicanilide PET Imaging of Altered Histone Deacetylase Activity in Chemotherapy-Induced Neurotoxicity

BACKGROUND: Histone deacetylases (HDACs) regulate gene expression by changing histone deacetylation status. Neurotoxicity is one of the major side effects of cisplatin, which reacts with deoxyribonucleic acid (DNA) and has excellent antitumor effects. Suberoylanilide hydroxamic acid (SAHA) is an HDA...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Contrast Media Mol Imaging
Main Authors: Fukumitsu, Nobuyoshi, Yeh, Skye Hsin-Hsien, Flores II, Leo Garcia, Mukhopadhyay, Uday, Young, Daniel, Ogawa, Kazuma, Jeong, Hwan-Jeong, Tong, William, Gelovani, Juri G.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884410/
https://ncbi.nlm.nih.gov/pubmed/29755299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3612027
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares