VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2

We have previously shown that the transcript levels of Vegfc and its receptor Vegfr3 were high in spermatogonia and extremely low in spermatocytes and spermatids. However, it remains unknown about the functions and the mechanisms of VEGFC/VEGFR3 signaling in regulating the fate determinations of spe...

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Publicat a:Cell Cycle
Autors principals: Zhao, Liangyu, Zhu, Zijue, Yao, Chencheng, Huang, Yuhua, Zhi, Erlei, Chen, Huixing, Tian, Ruhui, Li, Peng, Yuan, Qingqing, Xue, Yunjing, Wan, Zhong, Yang, Chao, Gong, Yuehua, He, Zuping, Li, Zheng
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884123/
https://ncbi.nlm.nih.gov/pubmed/29169284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1407891
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