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Treatment options after virological failure of first line tenofovir-based regimens in South Africa: an analysis by deep sequencing

In a South African cohort of participants living with HIV developing virological failure on first-line TDF-based regimens, at least 70% of participants demonstrated TDF resistance according to combined Sanger and MiSeq(™) genotyping. Sanger sequencing missed the K65R mutation in 30% of samples. Unle...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Casadellà, Maria, Noguera-Julian, Marc, Sunpath, Henry, Gordon, Michelle, Rodriguez, Cristina, Parera, Mariona, Kuritzkes, Daniel R., Marconi, Vincent C., Paredes, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884087/
https://ncbi.nlm.nih.gov/pubmed/26807968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001033
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