High rate of K65R for ART naïve patients with subtype C HIV infection failing a TDF-containing first-line regimen in South Africa

OBJECTIVE: We sought to determine the rate of the K65R mutation in patients receiving tenofovir (TDF)-based antiretroviral treatment (ART) with subtype C HIV infection. DESIGN: Retrospective cohort study. METHODS: All patients initiated on d4T+3TC or TDF+3TC plus a NNRTI at McCord Hospital in Durban...

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Detalhes bibliográficos
Main Authors: Sunpath, Henry, Wu, Baohua, Gordon, Michelle, Hampton, Jane, Johnson, Brent, Moosa, Yunus, Ordonez, Claudia, Kuritzkes, Daniel R., Marconi, Vincent C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757561/
https://ncbi.nlm.nih.gov/pubmed/22739389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328356886d
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