Gaussian Curvature Directs Stress Fiber Orientation and Cell Migration

We show that substrates with nonzero Gaussian curvature influence the organization of stress fibers and direct the migration of cells. To study the role of Gaussian curvature, we developed a sphere-with-skirt surface in which a positive Gaussian curvature spherical cap is seamlessly surrounded by a...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Bade, Nathan D., Xu, Tina, Kamien, Randall D., Assoian, Richard K., Stebe, Kathleen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2018
Onderwerpen:
Cell Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883952/
https://ncbi.nlm.nih.gov/pubmed/29590603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.039
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