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Role of Suspended Fiber Structural Stiffness and Curvature on Single-Cell Migration, Nucleus Shape, and Focal-Adhesion-Cluster Length

It has been shown that cellular migration, persistence, and associated cytoskeletal arrangement are highly dependent on substrate stiffness (modulus: N/m(2) and independent of geometry), but little is known on how cells respond to subtle changes in local geometry and structural stiffness (N/m). Here...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Meehan, Sean, Nain, Amrinder S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255195/
https://ncbi.nlm.nih.gov/pubmed/25468339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.09.045
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