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A Computational Study of Stress Fiber-Focal Adhesion Dynamics Governing Cell Contractility

We apply a recently developed model of cytoskeletal force generation to study a cell’s intrinsic contractility, as well as its response to external loading. The model is based on a nonequilibrium thermodynamic treatment of the mechanochemistry governing force in the stress fiber-focal adhesion syste...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maraldi, M., Valero, C., Garikipati, K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017287/
https://ncbi.nlm.nih.gov/pubmed/24806921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.027
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