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ECM Cross-Linking Regulates Invadopodia Dynamics

Invadopodia are membrane protrusions dynamically assembled by invasive cancer cells in contact with the extracellular matrix (ECM). Invadopodia are enriched by the structural proteins actin and cortactin as well as metalloproteases such as MT1-MMP, whose function is to degrade the surrounding ECM. D...

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Foilsithe in:Biophys J
Main Authors: Pourfarhangi, Kamyar Esmaeili, Bergman, Aviv, Gligorijevic, Bojana
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883616/
https://ncbi.nlm.nih.gov/pubmed/29590602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.027
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