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ECM Cross-Linking Regulates Invadopodia Dynamics

Invadopodia are membrane protrusions dynamically assembled by invasive cancer cells in contact with the extracellular matrix (ECM). Invadopodia are enriched by the structural proteins actin and cortactin as well as metalloproteases such as MT1-MMP, whose function is to degrade the surrounding ECM. D...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Pourfarhangi, Kamyar Esmaeili, Bergman, Aviv, Gligorijevic, Bojana
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883616/
https://ncbi.nlm.nih.gov/pubmed/29590602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.027
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