Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation

The inherent tendency of proteins to convert from their native states into amyloid aggregates is associated with a range of human disorders, including Alzheimer’s and Parkinson’s diseases. In that sense, the use of small molecules as probes for the structural and toxic mechanism related to amyloid a...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Valiente-Gabioud, Ariel A., Riedel, Dietmar, Outeiro, Tiago F., Menacho-Márquez, Mauricio A., Griesinger, Christian, Fernández, Claudio O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2018
Schlagworte:
Proteins
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883547/
https://ncbi.nlm.nih.gov/pubmed/29539391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.003
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