MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

BACKGROUND: By regulating target genes, microRNAs play essential roles in carcinogenesis and drug resistance in human pancreatic ductal adenocarcinoma (PDAC). Previous studies have shown that microRNA-10a-5p (miR-10a-5p) is overexpressed in PDAC and acts as an oncogene to promote the metastatic beha...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Xiong, Guangbing, Huang, Hua, Feng, Mengyu, Yang, Gang, Zheng, Suli, You, Lei, Zheng, Lianfang, Hu, Ya, Zhang, Taiping, Zhao, Yupei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883523/
https://ncbi.nlm.nih.gov/pubmed/29615098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0739-x
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